Metal-Free Decarboxylative A3 -Coupling/Pictet-Spengler Cascade Accessing Polycyclic Scaffolds: Propiolic Acids Exceed Alkynes
نویسندگان
چکیده
منابع مشابه
Metal-free intramolecular oxidative decarboxylative amination of primary α-amino acids with product selectivity.
A novel metal-free intramolecular oxidative decarboxylative coupling of primary α-amino acids with 2-aminobenzoketones under mild and neutral conditions was developed. Different quinazolines can be selectively obtained by various oxidants.
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Constructing products of high synthetic value from inexpensive and abundant starting materials is of great importance. Aryl iodides are essential building blocks for the synthesis of functional molecules, and efficient methods for their synthesis from chemical feedstocks are highly sought after. Here we report a low-cost decarboxylative iodination that occurs simply from readily available benzo...
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ژورنال
عنوان ژورنال: European Journal of Organic Chemistry
سال: 2020
ISSN: 1434-193X
DOI: 10.1002/ejoc.202000007